Custom Peptides
Cayman Chemical Endosulfn II 10mg
An organochlorine insecticide; active against a variety of insects including bollworms and tobacco budworms (LD50s = 4.14 and 4.95 mg/g, respectively); binds to GABA receptors (IC50 = 60 nM in rat brain membranes); toxic to rats (LD50 = 240 mg/kg)
Cayman Chemical cIstrIsmethoxy RSvRatrol 10mg
A potent anti-mitotic drug that is 100-fold more active than resveratrol at inhibiting the growth of human colon cancer Caco-2 cells; inhibits tubulin polymerization in a dose-dependent manner (IC50 = 4 μM) and enzymes involved in the synthesis of the polyamines, putrescine, and spermidine
Cayman Chemical aEthylamInopentIophenonhy 10mg
A substituted cathinone that is an analog to ethcathinone, differing by having propyl rather than methyl at the α position; intended for forensic and research purposes.
Cayman Chemical SitosterolDglucoside 10mg
A sterol glycoside with diverse biological activities; active against E. coli and S. aureus; inhibits α-amylase and α-glucosidase and scavenges DPPH radicals (IC50s = 46.4, 17, and 155 µM, respectively); inhibits the proliferation of HepG2 and SMMC-7721 hepatocellular carcinoma cells (IC50s = 143.4 and 138.73 UG/ml, respectively) and migration and invasion in the same cells at 50 or 100 UG/ml; increases survival and decreases the number of kidney CFUs in a mouse model of candidiasis induced by C. albicans
Cayman Chemical 5 6-epoxy Cholestnol 10mg
An oxidative metabolite of cholesterol; formed via radical and non-radical oxidation of cholesterol at the 5,6-double bond; induces release of LDH and apoptosis in macrophage-differentiated U937 cells; has been found in human fatty streaks and advanced atherosclerotic lesions
Cayman Chemical 6aMethylprednIsoLN 21hemI 10mg
A prodrug form of methylprednisolone; nanoliposomes containing 6α-methylprednisolone 21-hemisuccinate decrease disease severity in a rat model of adjuvant-induced arthritis
Cayman Chemical NIcotInamID rIbosIDd4trI 10mg
An internal standard for the quantification of nicotinamide riboside by GC- or LC-MS
Cayman Chemical TrImetazIdInd8hydrochLRI 10mg
An internal standard for the quantification of trimetazidine by GC- or LC-MS
Cayman Chemical OxytocInacetate 10mg
A nonapeptide hormone primarily synthesized in the hypothalamus with roles in uterine contraction and lactation, social memory and attachment, sexual and maternal behavior, aggression, learning, anxiety, feeding, and pain perception
Cayman Chemical ncrostatIn-1 10mg
An inhibitor of RIP1 kinase that prevents the death of TNF-α-treated FADD-deficient Jurkat cells with an EC50 value of 490 nM
Cayman Chemical IdarubIcInhydrochlorIde 10mg
A 4-demethoxy analog of daunorubicin which intercalates in DNA and inhibits topoisomerase II, resulting in cancer cell cytotoxicity at low concentrations (IC50 = 20-120 nM); effective in combination therapy for the treatment of different types of leukemia
Cayman Chemical 13 14epoxy FlupROSnl Isop 10mg
An impurity generated in the production of travoprost; a 4:96 diastereomeric mixture of epoxides
Cayman Chemical BromosporIn 10mg
A non-selective bromodomain inhibitor that at 1 µM has been shown to accelerate FRAP recovery of BRD4 and CREBBP bromodomains in HeLa cells
Cayman Chemical LInaclotIde 10mg
A peptide agonist of the guanylate cyclase C receptor (Ki = 16.4 nM in a radioligand binding assay using mouse intestinal mucosa); stimulates fluid secretion and cGMP concentration in jejunal loops isolated from wild-type mice but not guanylate cyclase C receptor-null mice; increases intestinal transit rate in wild-type mice when administered at a dose of 100 μg/kg; reduces the number of phosphorylated ERK-positive dorsal horn neurons in the thoracolumbar spinal cord, a marker of nociceptive signaling, following noxious colorectal distension and mechanical hypersensitivity in a mouse model of TNBS-induced colitis